Levafluke suspension is a broad spectrum anthelmintic combination contains levamisole hydrochloride as antinematoda and oxyclozanide as a fasciolicide in suspension form. Levamisole is the l isomer of dl-tetramisole. It has a paralyzing action on nematodes. The paralysis is due to sustained muscle contraction. Levamisole acts as a ganglion stimulant (cholinomimetic).
Oxyclozanide is a salicylanilide with specific activity against adult liver flukes. Its mode of action is based on alteration of phosphorylase link in energy metabolism of worm, and may also inhibit fumarate reductase activity.