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Ivermectin is an endectocide with activity against a wide range of internal and external parasites. It enhances the release of gamma amino butyric acid (GABA) at presynaptic neurons. GABA acts as an inhibitory neurotransmitter and blocks the post-synaptic stimulation of the adjacent neuron in nematodes or the muscle fiber in arthropods. By stimulating the release of GABA, ivermectin causes paralysis of the parasite and eventual death.
Clorsulon inhibits the glycolytic enzymes 3-phosphoglycerate kinase and phosphoglyceromutase, thereby blocking the Emden-Myerhof glycolytic pathway. The fluke is deprived of its main metabolic energy source and dies.
تنبيه بخصوص المعلومات المتوفرة علي موقع دراج فيت
