synthetic anticoccidial is effective against all species of Eimeria as evidenced by greater suppression of lesions in the intestines compared with other drugs. Diclazuril is also able to completely suppress oocyst production thereby reducing the risk of subclinical infection. It is therefore ideal for reducing infection levels or “cleaning-up” commercial houses.

When used in rotation programs with other anticoccidials, diclazuril will not only improve efficacy, but its “clean-up” effect should help improve the efficacy of other drugs. This is important because other feed additives used for coccidiosis control – ionophorous antibiotics such as salinomycin, monensin, narasin and semduramicin “belong to the same family of drugs and have a similar mode of action. As a result, strains of coccidia resistant to one drug show reduced sensitivity to the others.
Diclazuril is effective against ionophore-resistant strains and strains resistant to various “chemical” drugs such as amprolium, clopidol, robenidine, halofuginone
For best results, diclazuril should be used for no more than two successive flocks before rotating to an ionophore or a chemical/ionophore shuttle program; e.g., nicarbazin followed by salinomycin in starter and grower feeds
It is important to include diclazuril in the starter ration to reduce the build-up of oocysts in the litter. Although lesions due to Eimeria are not often seen before 3 weeks of age Diclazuril can also be included in the grower ration because this is the period when the pathogenic effects of coccidiosis are most likely. Another reason to include diclazuril in both feeds is to eliminate any resistant strain
Diclazuril has a strong cidal action against the later stages of Eimeria but allows the early, immunogenic stages to develop. Will not interfere with the formation of natural immunity
provides maximum protection against clinical coccidiosis outbreaks and allows a normal
development of intestinal microflora.Because of the strong coccidiocidal effect, the product also contributes