Neomycin: is an aminoglycoside bactericidal antibiotic that its antimicrobial action results from the fixation of the 30 subunit of ribosomes. olso disturbs the bacterial membrane permeability.

Neomycin: active against gram {-} negative and gram (+) positive bacteria, such as Escherichia coli, staphylococcus aureus, Klebsiella pneumoniae, streptococcus faecalis, Haemophilus influenzae, Mycobacterium tuberculosis,proteus vulgaris, Bacillus anthracis, Salmonella spp .And Shigella spp.